主要業績:

• 見尾光庸「抗炎症薬，抗リウマチ薬，痛風治療薬」，佐藤進編『新薬理学テキスト〔第3版〕』，廣川書店（2011）
• 見尾光庸，小駒益弘，福井裕行，竹田篤「ナノ粒子による炎症性伝達物質吸着を利用した炎症制御の研究」，『ケミカルエンジニヤリング』，第55巻(2010)
• Satomi A, Mio M, Tanaka K, Kogoma M “Silica nano powder formation using ICP plasma and evaluation of its adsorption ability for biotic substances”, J Photopolymer Sci Tech, 21 (2008)
• Takatori S, Zamami Y, Yabumae N, Hanafusa N, Mio M, Egawa T, Kawasaki H “Pioglitazone opposes neurogenic vascular dysfunction associated with chronic hyperinsulinaemia”, Br J Pharmacol, 153 (2008)
• Zamami Y, Takatori S, Yamawaki K, Miyashita S, Mio M, Kitamura Y, Kawasaki H. “Acute hyperglycemia and hyperinsulinemia enhance adrenergic vasoconstriction and decrease calcitonin gene-related peptide-containing nerve-mediated vasodilation in pithed rats”, Hypertens Res, 31 (2008)

その他の業績はresearchmapの研究者情報へ

主要業績:

• Okuda J, Kiriyama M, Suzaki E, Kataoka K, Nishibuchi M, Nakai T, “Characterization of proteins secreted from a type III secretion system of Edwardsiella tarda and their roles in macrophage infection”, Disease of Aquatic Organisms, 84 (2009).
• Suzaki E, Nomura R, Horio T, Mineyuki Y, Kataoka K, “γ-tubulin-like molecules in the mouse duodenal epithelium”, Histochemistry and Cell Biology, 128 (2007).
• Kataoka K, Suzaki E, Ajima N, “The Hoshino wooden skeleton, the first wooden model of a human skeleton, made during the Edo era in Japan”, Anatomical Science International, 82 (2007).
• Suzaki E, Wang G, Cao G, Wang H-Q, Englander EW, Greeley Jr. GH, “Apelin cells in the rat stomach”, Regulatory Peptides, 129 (2005).
• Suzaki E, Suzaki T, Kataoka K, “Use of Taxol and collagenase for better three-dimensional visualization of microtubules in the enterocyte and Brunner’s gland cell, with special reference to their relation to the Golgi apparatus”, Journal of Electron Microscopy, 53 (2004)

その他の業績はresearchmapの研究者情報へ

主要業績:

• Niwa T, Toyota M, Kawasaki H, Ishii R, Sasaki S. “Comparison of the stimulatory and inhibitory effects of steroid hormones and α-naphthoflavone on steroid hormone hydroxylation catalyzed by human cytochrome P450 3A subfamilies”. Biol Pharm Bull. 44, 579-584 (2021).
• Niwa T, Okamoto A, Narita K, Toyota M, Kato K, Kobayashi K, Sasaki S. “Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies”. Arch Biochem Biophys. 682, 108283 (2020).
• Niwa T, Sugimoto S. “Inhibitory and stimulatory effects of selective serotonin reuptake inhibitors on cytochrome P450 2D6-mediated dopamine formation from p-tyramine”. J Pharm Pharm Sci. 22, 585-592 (2019).
• Niwa T, Narita K, Okamoto A, Murayama N, Yamazaki H. “Comparison of steroid hormone hydroxylations by and docking to human cytochromes P450 3A4 and 3A5”. J Pharm Pharm Sci. 22, 332-339 (2019).
• Niwa T, Shizuku M, Yamano K., "Effect of genetic polymorphism on the inhibition of dopamine formation from p-tyramine catalyzed by brain cytochrome P450 2D6", Arch Biochem Biophys, 620, 23-27 (2017).

その他の業績はresearchmapの研究者情報へ

主要業績:

• 山田陽一，阿山未来，小林美穂，和田朋子，工藤季之， 杉山哲大，塩田澄子　MRSAの病原因子遺伝子保有状況調査から見出されたリスクファクターをもつ CA-MRSA の性状解析Characterization of community-acquired Methicillin-resistant Staphylococcus aureus (CA-MRSA) with the high risk factors found from the toxigenic gene profile from clinical isolates　就実大学薬学雑誌 第6巻ｐ50-54（2019）
• Hisatsune J, Hagiya H, Shiota S, Sugai M. Complete Genome Sequence of Systemically Disseminated Sequence Type 8 Staphylococcal Cassette Chromosome mec Type IVl Community-Acquired Methicillin-Resistant Staphylococcus aureus. M. Genome Announc. 2017 Aug 31;5(35)(2017)
• 和田朋子, 山田陽一, 近藤祥代, 杉山哲大, 塩田澄子.　臨床現場における市中感染型 MRSA の増加とバイオフィルム形成能の関連　Relation between the increase of the isolation number of Community-Acquired MRSA and their biofilm formation. 就実大学薬学雑誌第4巻p16-22（2017）
• Hagiya H, Haruki Y, Uchida T, Wada T, Shiota S, Ishida T, Ogawa H, Murase T, Otsuka F. Emergence of Daptomycin-Resistant Staphylococcus aureus during Treatment. Intern Med.;55(1):73-78.（2016）
• Hagiya H, Hisatsune J, Kojima T, Shiota S, Naito H, Hagioka S, Morimoto N, Otsuka F, Sugai, M. Comprehensive analysis of systemically disseminated ST8/non-USA300 type community-acquired methicillin-resistant Staphylococcus aureus infection. Intern Med., 53(8):907-912. (2014)

その他の業績はresearchmapの研究者情報へ

主要業績:

• Sayuri Sakamoto, Etsuko Suzaki, Osamu Hiraoka＊ Expression and purification of EF-hand endoplasmic reticulum-resident calcium-binding protein from Plasmodium falciparum using the E. coli Lemo21 (DE3) strain SHUJITSU RONSO No.47 PP.289-297 (2018)
• Osamu Hiraoka, Seita Ando, Yuhki Suemune, Kenichi Shimada, Masao Akamatsu,Scientific study of ease of removal of tablets from PTP sheet J Community Pharm Pharm Sci. Vol.9 No.2, 219-226 (2017)
• Osamu Hiraoka, Takuya Terai, Moe Kohno, Shigeru Sugiyama. Genetically engineered monomeric streptavidin for designing a new detection systems based on monovalent biotin interaction. The Shujitsu University Journal of Pharmaceutical Sciences Volume 3, 16-26 (2016)
• Sugiyama S., Shimizu N., Kakinouchi K., Hiraoka O., Matsumura H., Yoshikawa H.Y., Takahashi Y., Maruyama M., Yoshimura M., Adachi H., Takano K., Murakami S., Inoue T., Murata M. and Mori Y. Development of protein seed crystals reinforced with high-strength hydrogels. CrystEngComm. 17, 8064-8071 (2015)
• Hiraoka O, Hiraoka K. A Study of Pharmacists’ Job Satisfaction, Organizational Commitment, and Social Support in Organizational Management. The Shujitsu University Journal of Pharmaceutical Sciences Volume 2, 63-67 (2015)

その他の業績はresearchmapの研究者情報へ

主要業績:

• 抗てんかん薬TDM標準化ガイドライン 2018, 編集:一般社団法人 日本TDM学会, 分担，末丸克矢：ゾニサミド, ラモトリギン, 金原出版 (2018年)
• 新しい疾患薬理学,編集: 岩崎克典/徳山尚吾, 分担，末丸克矢：7章 代謝系・内分泌系の疾患と治療薬; A　糖尿病・代謝系内科領域の疾患に用いる薬物 (1糖尿病, 2脂質異常症, 3高尿酸血症・痛風) 南江堂 (2018年).
• Suemaru K, Yoshikawa M, Tanaka A, Araki H, Aso H, Watanabe M. Anticonvulsant effects of acetaminophen in mice. Comparison with the effects of nonsteroidal anti-inflammatory drugs. Epilepsy Res. 140: 22-28 (2018).
• Suemaru K, Yoshikawa M, Aso H, Watanabe M. TRPV1 mediates the anticonvulsant effects of acetaminophen in mice. Epilepsy Res. 145: 153-159 (2018).
• Suemaru K, Yoshikawa M, Aso H, Watanabe M. Environmental enrichment alleviates cognitive and behavioral impairments in EL mice. Epilepsy Behav. 85: 227-233 (2018).

主要業績:

• Watanabe M, et al. “The C-terminal region of tumor necrosis factor like weak inducer of apoptosis is required for interaction with advanced glycation end products” Biotechnol Appl Biochem, 66: 254-260 (2019)
• Gao S, et al. “Histidine-rich glycoprotein ameliorates endothelial barrier dysfunction through regulation of NF-κB and MAPK signal pathway” Br J Pharmacol, 176: 2808-2824 (2019)
• Gao Y, et al. “Phagocytosis of advanced glycation end products (AGEs) in macrophages induces cell apoptosis” Oxid Med Cell Longev, doi: 10.1155/2017/8419035. (2018)
• Kuroda K, et al. “Decrease in histidine-rich glycoprotein as a novel biomarker to predict sepsis among systemic inflammatory response syndrome” Critical Care Medicine, 46: 570-576 (2018)
• Watanabe M, et al. “ Advanced glycation end products attenuate the function of tumor necrosis factor-like weak inducer of apoptosis to regulate the inflammatory response” Mol Cell Biochem, 434: 153-162 (2017)

その他の業績はresearchmapの研究者情報へ

主要業績:

• Yokogawa, et al. Early onset hydroxychloroquine retinopathy and a possible relationship with blood level: comment on the article Petri et al. Arthritis and Rheumatology.73(2): 358-359. doi: 10.1002/art.41497 (2021).
• Kido K, et al. Meta-analysis comparing direct oral anticoagulants versus warfarin in morbidly obese patients with atrial fibrillation. Am J Cardiol. 126(1): 23-28. doi: 10.1016/j.amjcard.2020.03.048 (2020).
• Matsuoka K, et al. Factors contributing to the systemic clearance of Infliximab with long-term administration in Japanese patients with Crohn’s disease: Analysis using population pharmacokinetics. Int J Clin Pharmacol Ther. 58(2): 89-102. doi: 10.5414/CP203569 (2019).
• Akiyama S, et al. Long-term effect of NUDT15 R139C on hematologic indices in inflammatory bowel disease patients treated with thiopurine. J. Gastroenterol. Hepatol. 34(10): 1751-1757. doi: 10.1111/jgh.14693 (2019).
• Matsuoka K, et al. Factors predicting the therapeutic response to infliximab during maintenance therapy in Japanese patients with Crohn's disease. PLoS One. 13(10): e0204632, doi: 10.1371/journal.pone.0204632 (2018).

主要業績:

• Sugiura S, Kitamura Y, Izushi Y, Ushio S, Sendo T. Factors associated with work efficiency in home health care by pharmacists. Acta Medica OKAYAMA 2022; 76: 307-315.
• Uchida M, Ushio S, Niijima T, Takechi K, Kawazoe H, Hidaka N, Tanaka A, Araki H, Zamami Y, Ishizawa K, Kitamura Y, Sendo T, Kawasaki H, Namba H, Shibata K, Tanaka M, Takatori S. Renin-Angiotensin-Aldosterone System Inhibitors Prevent the Onset of Oxaliplatin-Induced Peripheral Neuropathy: A Retrospective Multicenter Study and in Vitro Evaluation. Biol Pharm Bull. 2022; 45: 226-234.
• Tabuchi H, Kitamura Y, Ushio S, Kan S, Wada Y, Sumiyoshi Y, Izushi Y, Miyazaki I, Asanuma M, Sendo T. Influence of 5-HT2A receptor function on anxiety-like behavior induced by combination treatment with doxorubicin and cyclophosphamide in rats. Psychopharmacology 2021; 238:3607-3614.
• Matsumoto D, Ushio S, Wada Y, Noda Y, Esumi S, Izushi Y, Kitamura Y, Sendo T. Bumetanide prevents diazepam-modified anxiety-like behavior in lipopolysaccharide-treated mice. Eur J Pharmacol. 2021 Aug 5;904:174195. doi: 10.1016/j.ejphar.2021.174195.
• Kameda S, Kitamura Y, Masaoka Y, Fujimoto M, Ushio S, Sendo T. Investigation of the difficulties experienced by pharmacists in Japan when communicating with cancer patients. J Clin Pharm Ther. 2021; 46:181-189.

その他の業績はresearchmapの研究者情報へ

ORCIDの研究者情報

Scopusの研究者情報

研究室ホームページ

主要業績:

• ShioriNishiuchi, KentaYagi, HiroumiSaito, YoshitoZamami, TakahiroNiimura, KojiMiyata, YoshikaSakamoto, KimikoFukunaga, ShunsukeIshida, HirofumiHamano, FukaAizawa, MitsuhiroGoda, MasayukiChuma, YukiIzawa-Ishizawa, HidekiNawa, HiroakiYanagawa, YasunariKanda, KeisukeIshizawa; Investigation of drugs for the prevention of doxorubicin-induced cardiac events using big data analysis. European Journal of Pharmacology, (928), https://doi.org/10.1016/j.ejphar.2022.175083 (2022)
• Rei Nakayama, Hideki Nawa, Takayoshi Maiguma, Yuichi Tasaka; Analysis of the Possibility of Drug-Induced Aspiration Pneumonia Due to Anxiolytics by Using the Japanese Adverse Drug Event Report Database. BPB Reports, 5, (3) 39-41 (2022)
• Hideki Nawa, Takahiro Niimura, Hirofumi Hamano, Kenta Yagi, Mitsuhiro Goda, Yoshito Zamami, Keisuke Ishizawa; Evaluation of potential complications of Interstitial Lung Disease associated with antiandrogens using data from databases reporting spontaneous adverse effects. Frontiers in Pharmacology, (12) 10.3389/fphar.2021.655605. (2021)
• Hideki Nawa, Takahiro Niimura, Kenta Yagi, Mitsuhiro Goda, Yoshito Zamami, Keisuke Ishizawa; Evaluation of potential complication of interstitial lung disease with abemaciclib and palbociclib treatments. Cancer Reports. e1402. https://doi.org/10.1002/cnr2.1402. (2021)
• Triphasic vascular responses to bradykinin in the mesenteric resistance artery of the rat.
  Hideki Nawa, Hiromu Kawasaki, Akira Nakatsuma, Satiko Isobe, Yuji Kurosaki European Journal of Pharmacology ;433(1):105-113 (2001)

その他の業績はresearchmapの研究者情報へ

主要業績:

• 國府團，五味田裕編『薬剤師・看護師・医薬系学生のための臨床医薬略語集』，医歯薬出版，2010〔分担執筆〕
• 江川孝，谷口律子，柴田隆司，前田純子，小野浩重，島田憲一，五味田裕「PBL型コミュニケーション演習における模擬患者の積極的活用と演習内容の評価」，『医療薬学』第36巻（2010）
• Tadatsugu Tarumi, Azusa Mikami, Kenichi Shimada Chiaki Kamei,”Participation of the Cholinergic System in Ameliorating Effect of Vasopressin Fragment by Group I Metabotropic Glutamate Receptor Blockade”,J Pharmacol Sci.,3(2008)
• 塚田由美子，見市昇，荒木雅史，吉野公博，北浦道夫，木口亨，木村圭吾，善家雄吉，島田憲一 他「ノロウィルスアウトブレイクに対する組織的な取り組み」，『香川労災病院雑誌』第14巻（2008）
• 木口亨，各務慎一，滝本秀隆，島田憲一　他B細胞性前リンパ球性白血病の1例」，『香川県内科医会誌』第43巻（2007）

主要業績:

• チーム基盤型学習（TBL）実施に向けた取り組みとその評価
  加地弘明、山﨑勤、吉川弥里、山田陽一、他
  就実大学薬学雑誌　第7巻　69-75（2020）
• 在宅医療において薬剤師に求められる役割に関する医療介護系多職種の意識調査～福山在宅どうしよう会での活動を通して～
  加地弘明、弘中沙樹、平田悟史、小野浩重
  就実大学薬学雑誌　第5巻　47-51（2018）
• Kawakami T, He J, Morita H, Yokoyama K, Kaji H, Tanaka C, Suemori S, Tohyama K, Tohyama Y, “Rab27a is essential for the formation of neutrophil extracellular traps(NETS) in neutrophil-like differentiated HL60 cells” PLOS ONE. 9(1), e84704 (2014)
• Shinichi Watanabe; Katsuya Suemaru, PhD; Kenshi Takechi, PhD; Hiroaki Kaji, PhD; Kimie Imai, PhD; Hiroaki Araki, PhD, “Oral mucosal adhesive films containing royal jelly accelerate recovery from 5-fluorouracil-induced oral mucositis” Journal of Pharmacological Sciences, 121, 110-118 (2013)
• Tanaka K, Ogo H, Kaji H, Miyatake K, Tokudome E, Sonoda K, Ogawa N, Asanuma M. “Dipeptidyl compounds ameliorate the serum-deprivation-induced reduction in cell viability via the neurotrophin-activating effect in SH-SY5Y cells.” Neurol Res. Jul;34(6):619-22 (2012)

主要業績:

• Maiguma T, Komoto A, Shiraga E, Hagiwara S, Onishi J, Li M, Teshima D. Influence of Pharmacist Intervention on Re-Elevation of Glycated Hemoglobin for Diabetic Outpatients. Hospital Pharmacy. https://doi.org/10.1177/0018578719883806 (2019)
• 白髪, 大西, 廣本, 李, 手嶋, 毎熊. 外来糖尿病患者に対する「薬剤師外来」の成果. 医療薬学, 45, 135-142 (2019)
• Komoto A, Maiguma T, Teshima D, Sugiyama T, Haruki Y. Effects of pharmacist intervention in Vancomycin treatment for patients with bacteremia due to Methicillin-resistant Staphylococcus aureus. PLoS One, 13, e0203453 (2018)
• 増田, 毎熊, 広本, 春木, 杉山, 手嶋. 抗菌薬TDMガイドライン2016におけるバンコマイシン初期投与設計に対するeGFRを用いたノモグラムの検証－軽度から中等度の腎機能低下患者における検討－. TDM研究, 34, 132-136 (2017)
• 渡辺, 毎熊, 難波, 山崎, 高取, 広本, 賀勢, 今井, 安藤, 手嶋. 療養病棟における入院9週目以降での薬剤師の介入効果―病棟薬剤業務における処方提案―. 医療薬学. 42(8), 551-557 (2016)

その他の業績はresearchmapの研究者情報へ

主要業績:

• Watanabe M, Toyomura T, Wake H, Liu K, Teshigawara K, Takahashi H, Nishibori M, Mori S. “The C-terminal region of tumor necrosis factor like weak inducer of apoptosis is required for interaction with advanced glycation end products.” Biotechnol. Appl. Biochem. 66 (2019)
• Watanabe M, Toyomura T, Wake H, Liu K, Teshigawara K, Takahashi H, Nishibori M, Mori S. “Advanced Glycation End Products Attenuate the Function of Tumor Necrosis Factor-like Weak Inducer of Apoptosis to Regulate the Inflammatory Response.” Mol. Cell Biochem. 434 (2017)
• 森秀治、渡邊政博、豊村隆男“自然免疫センサーとしてのパターン認識受容体の病態生理学的意義” 就実大学薬学雑誌 3（2016）
• Sun-Wada G.-H., Toyomura T., Murata Y., Yamamoto A., Futai M., and Wada Y. “The a3 isoform of V-ATPase regulates insulin secretion from pancreatic β-cells.”J. Cell Sci. 119 (2006)
• Toyomura T., Murata Y., Yamamoto A., Oka T., Sun-Wada G.-H., Wada Y., and Futai M.”From lysosomes to the plasma membrane: localization of vacuolar-type H+-ATPase with the a3 isoform during osteoclast differentiation.” J. Biol. Chem. 278 (2003)

その他の業績はresearchmapの研究者情報へ

主要業績:

• 抗ウイルス対策表面創成へのアプローチとセラミックスコーティング、山田　陽一、上田　剛慈、明渡　純、セラミックス、4： 222-229 （2021）
• Report of English Language and Pharmacy Program 2019 in Australia, Yoichi Yamada, Hiroaki Aso, Hiroaki Kaji, Kei Moriyama, Takao Toyomura, Minako Matsuo, Tohru Nakanishi, The Shujitsu University journal of pharmaceutical sciences, 8: 81-84 (2021)
• Isolation and identification of a compound showing anti-Staphylococcal activity., N. Ohtaguro, H. Matsuo, K. Iwasaki, S. Ueda, K. Nakagawa, T. Tsuchiya, N. Imamura, T. Dohi, Y. Yamada*, S. Shiota (*corresponding author), The Shujitsu University journal of pharmaceutical sciences, 8: 70-74 (2021)
• Reduction of benzalkonium chloride-resistant mutants of Pseudomonas aeruginosa PAO1 in the absence of benzalkonium chloride, Y. Yamada, D. Ueda, T. Kudo, T. Tsuchiya, S. Shiota, The Shujitsu University journal of pharmaceutical sciences, 7: 28-36 (2020)
• Characterization of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) with the high risk factors found from the toxigenic gene profile from clinical isolates, Yoichi Yamada, Miku Ayama, Miho Kobayashi, Tomoko Wada, Toshiyuki Kudo, Tetsuhiro Sugiyama, Sumiko Shiota, The Shujitsu University journal of pharmaceutical sciences, 6: 50-54, (2019)

主要業績:

• Watanabe M, Toyomura T, Wake H, Nishinaka T, Hatipoglu OF, Takahashi H, Nishibori M, Mori S. Identification of ribosomal protein L9 as a novel regulator of proinflammatory damage-associated molecular pattern molecules. Mol Biol Rep, Vol. 49, No.4, pp. 2831–2838 (2022)
• Watanabe M, Toyomura T, Tomiyama M, Wake H, Liu K, Teshigawara K,Takahashi H, Nishibori M, Mori S. Advanced glycation end products (AGEs) synergistically potentiated the proinflammatory action of lipopolysaccharide (LPS) and high mobility group box-1 (HMGB1) through their direct interactions. Mol Biol Rep, Vol. 47, No. 9, pp. 7153–7159 (2020)
• Watanabe M, Toyomura T, Wake H, Liu K, Teshigawara K, Takahashi H,Nishibori M, Mori S. Advanced Glycation End Products Attenuate the Function of Tumor Necrosis Factor-like Weak Inducer of Apoptosis to Regulate the Inflammatory Response. Mol Cell Biochem, Vol. 434, No. 1, pp. 153-162 (2017)
• Watanabe M, Fukuoka N, Takeuchi T, Yamaguchi K, Motoki T, Tanaka H,Kosaka S, Houchi H. Developing Population Pharmacokinetic Parameters for High-dose Methotrexate Therapy: Implication of Correlations among Developed Parameters for Individual Parameter Estimation Using the Bayesian Least-squares Method. Biol Pharm Bull, Vol. 37, No. 6, pp.916-921 (2014)
• Watanabe M, Yamamoto T, Kakuhata R, Okada N, Kajimoto K, Yamazaki N,Kataoka M, Baba Y, Tamaki T, Shinohara Y. Synchronized changes in transcript levels of genes activating cold exposure-induced thermogenesis in brown adipose tissue of experimental animals. Biochim Biophys Acta, Vol. 1777, No. 1, pp. 104-112 (2008)

その他の業績はresearchmapの研究者情報へ

主要業績:

• Rei Nakayama, Hideki Nawa, Takayoshi Maiguma, Yuichi Tasaka, Analysis of the possibility of drug-induced aspiration pneumonia due to anxiolytics by using the Japanese Adverse Drug Event Report database. BPB Reports. 2022 (in press)
• 竹内はる香, 立野朋志, 尾上洋, 廣田美祐紀, 廣戸敬毅, 監物英男, 伊達元英, 田坂祐一. 薬局プレアボイドの分析に基づく外来患者における薬剤関連問題の特徴　医療薬学, 48(5), 194–202, 2022
• 岡夏未, 近藤真志, 松原秀樹, 出石啓治, 田坂祐一, 3種類以上の薬剤服用時の薬物間相互作用に関する後方視的検討～岡山県児島地区の保険薬局における多施設共同研究～　YAKUGAKU ZASSHI, 141(7), 979–984, 2021
• Aisa Tanaka, Yuichi Tasaka, Haruka Takeuchi, Emina Teramoto, Natsumi Oka, Noriaki Hidaka, Akihiro Tanaka, Hiroaki Araki, Effects of trazodone on motor coordination and balance alterations following thiopental-induced anesthesia in mice. 就実大学薬学雑誌, 8, 75-80, 2021
• Yuichi Tasaka, Akihiro Tanaka, Daiki Yasunaga, Takashige Asakawa, Hiroaki Araki, Mamoru Tanaka, Potential drug-related problems detected by routine pharmaceutical interventions: safety and economic contributions made by hospital pharmacists in Japan. J Pharm Health Care Sci. 4:33, eCollection, 2018

その他の業績はresearchmapの研究者情報へ

臨床研究について

主要業績:

• 原（野上）愛：疾患薬理学テキスト，岩崎・徳山編，炎症・アレルギー・自己免疫疾患の章を担当，南江堂 (2018)
• Nogami-Hara A, Nagao M, Takasaki K, et al. The Japanese Angelica acutiloba root and yokukansan increase hippocampal acetylcholine level, prevent apoptosis and improve memory in a rat model of repeated cerebral ischemia. Journal of Ethnopharmacology. 214(25): 190-196 (2018)
• Nogami-Hara A, Handa A, Mitsuhata C, et al. Allergic activation of RBL-2H3 mast cells with L-Asparaginase and its inhibition by anti-IgE antibody. The Japanese Journal of Pediatric Hematology/Oncology, 54(4): 295 (2017)
• 原（野上）愛：第58回日本小児血液・がん学会学術集会，優秀ポスター賞受賞（2017）
• 日本生薬学会論文賞受賞 (2012)

主要業績:

• Tagashira H*, Izushi Y* (*: co-first author), Ikuta T, Koike Y, Kitamura Y and Yamamoto H.Regimen of 5-fluorouracil and cisplatin increases the risk of extravasation in patients undergoing chemotherapy
  IN VIVO. 35: 1411-1145 (2021).
• Morii C*, Tanaka HY* (*: co-first author), Izushi Y, Nakao N, Yamamoto M, Matsubara H, Kano MR and Ogawa A. 3D in vitro Model of Vascular　Medial Thickening in Pulmonary Arterial Hypertension
  Front Bioeng Biotechnol. 8:482 (2020).
• Izushi Y, Shiota N, Tetsunaga T, Shimada K, Egawa T, Kiuchi T, Sato T, Takuma R,·Takami Y. The clinical impact of edoxaban for the patients with postoperative anemia after total hip arthroplasty. Eur J Orthop Surg Traumatol. 28:1349–1358 (2018).
• Izushi Y, Teshigawara K, Liu K, Wang D, Wake H, Takata K, Yoshino T, Takahashi HK, Mori S, Nishibori M. Soluble form of the receptor for advanced glycation end-products attenuates inflammatory pathogenesis in a rat model of lipopolysaccharide-induced lung injury. J Pharmacol Sci. 130: 226-34 (2016).
• Izushi Y, Takami Y, Shiota N, Tetsunaga T, Ookura Y, Shimada K, Egawa T, Kiuchi T, Sato T, Takuma R. Clinical Assessment of Postoperative Anemia Associated with Edoxaban in Patients Undergoing Total Knee Arthroplasty Compared to Fondaparinux. Biol Pharm Bull. 39: 516-23 (2016).

主要業績:

• Kataoka H., Nakayama D., Online In-Tube Solid-Phase Microextraction Coupled with Liquid Chromatography–Tandem Mass Spectrometry for Automated Analysis of Four Sulfated Steroid Metabolites in Saliva Samples. Molecules, 27(10): 3225 (2022). (12 pages)
• Kataoka H., In-tube solid-phase microextraction: Current trends and future perspectives. J. Chromatogr. A, (Review article) 1636：461787 (2021). (26 pages)
• Kataoka H., Kaji S., Moai M., Risk Assessment of Passive Smoking Based on Analysis of Hair Nicotine and Cotinine as Exposure Biomarkers by In-Tube Solid-Phase Microextraction Coupled On-Line to LC-MS/MS. Molecules, 26(23): 7356 (2021). (10 pages).
• Kataoka H., Pharmaceutical Analysis/Sample Preparation, in Encyclopedia of Analytical Science 3 rd Edn, Edited by P. Worsfold, A.Townshend, C. Poole, M. Miró, (Elsevier: Amsterdam, Netherlands), Vol. 8, 231-255 (2019).
• Saito A., Hamano M., Kataoka H., Simultaneous analysis of multiple urinary biomarkers for the evaluation of oxidative stress by automated online in-tube solid-phase microextraction coupled with negative/positive ion-switching mode liquid chromatography−tandem mass spectrometry. J. Sep. Sci., 41: 2743-2749 (2018).

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ORCIDの研究者情報

主要業績:

• Mihara K, Kohno S, Hatanaka S, Yamasaki T, Nishida K, Nakanishi T. Identification of specific protein markers of rheumatoid arthritis in synovial fluid and serum. J Hard Tissue Biol 27, 55-58, 2018
• Fujimoto E, Matsushita Y, Nakajima T, Yagishita N, Yamasaki T, Nakanishi T. CD81 mediated regulation of synoviolin expression in synovial sarcoma cells. J Hard Tissue Biol 25, 377-382, 2016
• Nakagawa S, Arai Y, Mori H, Matsushita Y, Kubo T, Nakanishi T. Small interfering RNA targeting CD81 ameliorated arthritis in rats. Biochem Biophys Res Commun 388, 467-472, 2009
• Matsuoka Y, Yokoyama M, Kobayashi H, Omori M, Itano Y, Morita K, Mori H, Nakanishi T. Expression profiles of BDNF splice variants in cultured DRG neurons stimulated with NGF. Biochem Biophys Res Commun 362, 682-688, 2007
• Nakanishi T. Japan may seek embryo cells from overseas. Nature 405, 882, 2000

主要業績:

• S. Yamaori, Y. Okushima,K. Masuda, M. Kushihara, T. Katsu, S. Narimatsu, I. Yamamoto, K. Watanabe, “Structural requirements for potent direct inhibition of human cytochrome P450 1A1 by cannabidiol: Role of pentylresorcinol moiety”, Biological and Pharmaceutical Bulletin, 36(7) , 1197-1203 (2013)
• H. Kataoka, K. Saito, H. Kato ,K. Masuda, “Non-invasive analysis of volatile biomarkers in human emanations for health and early disease diagnosis”, Bioanalysis, 5(11), 1443-1459 (2013)
• H. Kataoka, T. Inoue, K. Saito, H. Kato, K. Masuda, “Analysis of heterocyclic amines in hair by on-line in-tube solid-phase microextraction coupled with liquid chromatography-tandem mass spectrometry”, Analytica Chimica Acta, 786, 54-60 (2013)
• K. Mayumi, N. Hanioka, K. Masuda, A. Koeda, S. Naito, A. Miyata, S. Narimatsu, “Characterization of marmoset CYP2B6: cDNA cloning, protein expression and enzymatic functions”, Biochemical Pharmacology, 85(8), 1182-1194 (2013)
• 勝 孝, 駒越圭子, 増田和文, 加藤久登, 井上 剛, “センサーを用いる薬物作用の in situ モニタリング”, BUNSEKI KAGAKU, 62(2), 121-130 (2013)

主要業績:

• Watanabe, M., Toudou, M., Uchida, T., Yoshikawa, M., Aso, H., Suemaru, K. (2019) Change in mutation frequency at a TP53 hotspot during culture of ENU-mutagenized human lymphoblastoid cells. Mutagenesis, in press.
• Mimaki, S., Watanabe, M., Kinoshita, M., Yamashita, R., Haeno, H., Takemura, S., Tanaka, S., Marubashi, S., Totsuka, Y., Shibata, T., Nakagama, H., Ochiai, A., Nakamori, S., Kubo, S., Tsuchihara, K. (2019) Multifocal origin of occupational cholangiocarcinoma revealed by comparison of multilesion mutational profiles. Carcinogenesis, in press.
• 渡辺雅彦、阿蘓寛明、吉川弥里、末丸克矢 (2019) 多段階クローン増殖モデルと乳がん：モデル推定と日本人女性の出生コホートとの比較　就実大学薬学雑誌　6, 17-30.
• Watanabe, M. (2016) Smoking: additional burden on aging and death. Genes Environment., 38:3.
• Nakano, T., Takahashi-Nakaguchi, A, Yamamoto, M. and Watanabe, M. (2015) Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish. Curr. Top. Microbiol. Immunol., 384, 127-149.

その他の業績はresearchmapの研究者情報へ

主要業績:

• Okamura A, Masumoto A, Takenouchi A, Kudo T, Aizawa S, Ogoshi M, Takahashi S, Tsudzuki M, Takeuchi S. Changes in prolactin receptor homodimer availability may cause late feathering in chickens. Gen Comp Endocrinol. 272: 109-116. (2019)
• Sutou S, Koeda A, Komatsu. K, Shiragiku T, Seki H, Yamakage K, Niitsuma T, Kudo T, Wakata A. Collaborative study of thresholds for mutagens: proposal of a typical protocol for detection of hormetic responses in cytotoxicity tests. Genes and Environ. 40: 20. (2018)
• Kudo T. Comparison of promoters for transient gene expression in avian cells. Proceeding of Okayama Association for Laboratory Animal Science 32: 28-22. (Japanese) (2016)
• Okutsu K, Ojima F, Shinohara N, Taniuchi S, Mizote Y, Aoki K, Kudo T, Ogoshi M, Takeuchi S, Takahashi S. Functional characterization of the mouse melanocortin 3 receptor gene promoter. Gene 562: 62-69. (2015)
• Ogo Y, Taniuchi S, Ojima F, Hayashi S, Murakami I, Saito Y, Takeuchi S, Kudo T, Takahashi S. IGF-1 Gene Expression is Differentially Regulated by Estrogen Receptors α and β in Mouse Endometrial Stromal Cells and Ovarian Granulosa Cells. J. Reprod. Dev. 60: 216-223. (2014)

その他の業績はresearchmapの研究者情報へ

主要業績:

• Otsuka C, Minami I, Oda K, “Hypoxia-inducible genes encoding small EF-hand proteins in rice and tomato”, Biosci Biotech Biochem, 74 (2010)
• Yung CW, Okugawa Y, Otsuka C, Okamoto K, Arimoto S, Loakes D, Negish K, ・Negishi T, ” Influence of neighbouring base sequences on the mutagenesis induced by 7,8-dihydro-8-oxoguanine in yeast”Mutagenesis, 2 (2008)
• Suzuki T, Moriyama K, Loakes D, Otsuka C, Negishi, K,” Template properties of mutagenic cytosine analogues in reverse transcription” Nucleic Acids Res, 34 (2006)

主要業績:

• KobayashiM., Akaki J., Ninomiya K., Yoshikawa M, Muraoka O., Morikawa T., Odawara M., Dose-Dependent Suppression of Postprandial Hyperglycemia and Improvement of Blood Glucose Parameters by Salacia chinensis Extract: Two Randomized, Double-Blind, Placebo-Controlled Studies., J. Med. Food, 24(1), 10-17 (2021).
• Takashima K., Sakano M., Nakamura S., Ishikawa F., Nakanishi I., Kinouchi E., Ninomiya K., Marumoto S., Morikawa T., Tanabe G., Elongation of the side chain by linear alkyl groups increases the potency of salacinol, a potent α-glucosidase inhibitor from the Ayurvedic traditional medicine "Salacia," against human intestinal maltase., Bioorg. Med. Chem. Lett., 33127751 (2021).
• Morikawa T., Inoue N., Nakanishi Y., Manse Y., Matsuura H., Okino K., Hamasaki S., Yoshikawa M., Muraoka O., Ninomiya K., Collagen synthesis-promoting and collagenase inhibitory activities of constituents isolated from the rhizomes of Picrorhiza kurroa Royle ex Benth., Fitoterapia, 143, 104584 (2020).
• Morikawa T., Luo F., Manse Y., Sugita H., Saeki S., Muraoka O., Ninomiya K., Chaipech S., Pongpiriyadacha Y., Geranylated Coumarins From Thai Medicinal Plant Mammea siamensis With Testosterone 5α-Reductase Inhibitory Activity., Front. Chem., 8199 (2020).
• Morikawa T., Nagatomo A., Oka T., Miki Y., Taira N., Shibano-Kitahara M., Hori Y., Muraoka O., Ninomiya K., Glucose tolerance-improving activity of helichrysoside in mice and its structural requirements for promoting glucose and lipid metabolism., Int. J. Mol. Sci., 20(24), 6322 (2019).

その他の業績はresearchmapの研究者情報へ

主要業績:

• *Yamashita Y, *Tanaka KI, *Yamakawa N (*equally contributed), Asano T, Kanda Y, Takafuji A, Kawahara M, Takenaga M, Fukunishi Y, Mizushima T. “Chemical modification-mediated optimisation of bronchodilatory activity of mepenzolate, a muscarinic receptor antagonist with anti-inflammatory activity”, Bioorg. Med. Chem., 27:3339-3346 (2019).
• Asano T, Hattori T, Tanaka KI, Yamakawa N, Suemasu S, Aida S, Kataoka M, Mizushima T, Takenaga M. “Antinociception by fluoro-loxoprofen, a novel non-steroidal anti-inflammatory drug with less ulcerogenic effects, in rat models of inflammatory pain”, Eur. J. Pharmacol., 5:253-258 (2019).
• *Tanaka KI, *Yamakawa N (*equally contributed), Yasunobu Y, Asano T, Kanda Y, Takafuji A, Kawahara M, Takenaga M, Fukunishi Y, Mizushima T. “Identification of mepenzolate derivatives with long-acting bronchodilatory activity” Front. Pharmacol., 10:344 (2018).
• Moriyama K, Furuno N, Yamakawa N. “Crystal face identification by Raman microscopy for assessment of crystal habit of a drug”, Int. J. Pharm., 480:101-106(2015).
• Yamakawa N, Suzuki K, Yamashita Y, Katsu T, Hanaya K, Shoji M, Sugai T, Mizushima T. “Structure-activity relationship of celecoxib and rofecoxib for the membrane permeabilizing activity”, Bioorg. Med. Chem., 22:2529-2534 (2014).

主要業績:

• Ishii H., Yokoyama A., Saito K., Kataoka H. : Synthesis and analytical differentiation of a novel synthetic cathinone 1-(2,3-dihydro-1H-inden-5-yl)-2-(pyrrolidin-1-yl)butan-1-one (5-PPDI) and its regioisomers. Forensic Chem.,27: 100393 (2022).
• Saito K., Tokorodani Y., Sakamoto C., Kataoka H. : Headspace solid-phase microextraction / gas chromatography-mass spectrometry for the determination of 2-nonenal and its application to body odor analysis. Molecules, 26: 5739 (2021).
• Hanioka N., Saito K., Isobe T., Ohkawara S., Jinno H., Tanaka‐Kagawa T. : Favipiravir biotransformation in liver cytosol: species and sex differences in humans, monkeys, rats, and mice. Biopharm. Drug Dispos., 42: 218-225 (2021).
• Kataoka H., Ishizaki A., Saito K., (2019) Online automated micro sample preparation for high-performance liquid chromatography. in Chromatography-Separation, Identification and Purification Analysis, Edited by N. Awwad, (InTech, Croatia), Chapter 9, 161-184.
• 『わかりやすい機器分析学』改訂第4版（廣川書店）2018年:　X線分析法、熱分析法　執筆担当.

その他の業績はresearchmapの研究者情報へ

主要業績:

• Yoshikawa M., Soeda Y., Michikawa M., Almeida OF., Takashima A.: Tau depletion in APP transgenic mice attenuates task-related hyperactivation of the hippocampus and differentially influences locomotor activity and spatial memory., Front. Neurosci., 12, 124 (2018)
• Suemaru K., Yoshikawa M., Tanaka A., Araki H., Aso H., Watanabe M.: Anticonvulsant effects of acetaminophen in mice: Comparison with the effects of nonsteroidal anti-inflammatory drugs. Epilepsy Res., 140, 22-28 (2018).
• Suemaru K., Yoshikawa M., Aso H., Watanabe M.: TRPV1 mediates the anticonvulsant effects of acetaminophen in mice. Epilepsy Res., 145, 153-159 (2018).
• Suemaru K., Yoshikawa M., Aso H., Watanabe M.: Environmental enrichment alleviates cognitive and behavioral impairments in EL mice. Epilepsy Behav., 85, 227-233 (2018).
• Soeda Y., Yoshikawa M, Almeida OF., Sumioka A., Maeda S., Osada H., Kondoh Y., Saito A., Miyasaka T., Kimura T., Suzuki M., Koyama H., Yoshiike Y., Sugimoto H., Ihara Y., Takashima A. Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups. Nat. Commun., 6:10216 (2015)

主要業績:

• K. Kawakami, C. Moritani, M. Uraji, A. Fujita, K. Kawakami, T. Hatanaka, E. Suzaki,S. Tsuboi. “ Hepatoprotective effects of rice-derived peptides against acetaminophen- induced damage in mice. ” , J. Clin. Biochem. Nutr., 60,115-120.(2017)
• K. Kawakami, P. Li, M. Uraji, T. Hatanaka, H. Ito. “ Inhibitory effects of pomegranate extracts on recombinant human maltase-glucoamylase.”, J. food sci., 79, H1848-53 (2014)
• K. Kawakami, H. Nishida, N. Tatewaki, K. Eguchi-Kasai, K. Anzai, T. Eitsuka, T.Konishi, M. Hirayama. “Persimmon ｌeaf ｆlavonols enhance the anti-cancer effect of heavy ion radiotherapy on murine xenograft tumors.” J. Cancer Therapy, 4,1150-7 (2013)
• K. Kawakami, S. Aketa, H. Sakai, Y. Watanabe, H. Nishida, M. Hirayama. “Antihypertensive and vasorelaxant effects of water-soluble proanthocyanidins from persimmon leaf tea in spontaneously hypertensive rats.” Biosci. Biotechnol.Biochem., 75, 1435-9 (2011)
• K. Kawakami, Y. Shibukura, T. Kanno, T. Furuki, S. Aketa, M. Hirayama.“ Identification of 2 ” -galloylated flavonol 3-O-glycosides accumulating in developing leaves of persimmon (Diospyros kaki Thunb.).” Phytochem. Anal., 22,403-10 (2011)

主要業績:

• H. Kato, K. Komagoe, T. Inoue, K. Masuda, T. Katsu, Structure–activity relationship of porphyrin-induced photoinactivation with membrane function in bacteria and erythrocytes, Photochem. Photobiol. Sci., 17, 954-963. (2018)
• H. Yamamura, M. Nonaka, S. Okuno, R. Mitsuhashi, H. Kato, T. Katsu, K. Masuda, K. Tanimoto, H. Tomita, A. Miyagawa, Membrane-active antimicrobial poly(aminomodified alkyl) β-cyclodextrins synthesized via click reactions, Med. Chem. Comm., 9, 509-518. (2018)
• 加藤久登，駒越圭子，勝 孝，片岡洋行， “クロリンによる細菌および赤血球の細胞膜機能の光不活性化”, 就実大学薬学雑誌, 3, 37-46, (2016)
• H. Kato, K. Komagoe, Y. Nakanishi, T. Inoue, T. Katsu, “Xanthene dyes induce membrane permeabilization of bacteria and erythrocytes by photoinactivation”, Photochem. Photobiol., 88, 423-431 (2012)
• H. Kato, K. Komagoe, T. Inoue, T. Katsu, “In situ monitoring of photodynamic inactivation of the membrane functions of bacteria using electrochemical sensors”, Anal. Sci., 26, 1019-1021 (2010)

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